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Hale Vene Transeksjon Blødning Modell i Fullt Bedøvet Hemofili En Mus
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Hale Vene Transeksjon Blødning Modell i Fullt Bedøvet Hemofili En Mus

Article DOI: 10.3791/62952-v • 08:13 min • September 30th, 2021
September 30th, 2021 •
1,2, 1, 1, 3, 1, 4, 5, 1, 6, 1
1Global Drug Discovery, Novo Nordisk A/S, 2Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 3Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 4Independent consultant, 5Catalyst Biosciences, 6Værløse Dyreklinik

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Den raffinerte hale vene transeksjon (TVT) blødning modell i bedøvede mus er en sensitiv in vivo metode for vurdering av hemofil blødning. Denne optimaliserte TVT blødningsmodellen bruker blodtap og blødningstid som endepunkter, raffinerer andre modeller og unngår døden som endepunkt.

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Biologi Utgave 175 hale vene transeksjon modell hale blødning dyr modell farmakologi intervensjon hemofili faktor FVIII slå ut mus
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