<em>In Vivo</em> Vascular Permeability Detection in Mouse Submandibular Gland

Xiangdi Mao; Sainan Min; Qihua He; Xin Cong

doi:10.3791/64167

Journal

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Biology

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In Vivo Vascular Permeability Detection in Mouse Submandibular Gland

<em>In Vivo</em> Vascular Permeability Detection in Mouse Submandibular Gland

JoVE Journal
Biology

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JoVE Journal Biology

In Vivo Vascular Permeability Detection in Mouse Submandibular Gland

In Vivo Vascular Permeability Detection in Mouse Submandibular Gland

1,943 Views

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07:10 min

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August 04, 2022

DOI:

10.3791/64167-v

DOI:

10.3791/64167-v

•

07:10 min

August 04, 2022

•

1923 Views

Xiangdi Mao¹, Sainan Min², Qihua He³, Xin Cong¹

¹Department of Physiology and Pathophysiology, Peking University School of Basic Medical Sciences, Key Laboratory of Molecular Cardiovascular Sciences,Ministry of Education, and Beijing Key Laboratory of Cardiovascular Receptors Research ²Department of Oral and Maxillofacial Surgery,Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Reseah Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices ³State Key Laboratory of Natural and Biomimetic Drugs,Peking University

Summary

In the present protocol, the endothelial barrier function of the submandibular gland (SMG) was evaluated by injecting different molecular weighted fluorescent tracers into the angular veins of test animal models in vivo under a two-photon laser-scanning microscope.