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Immunology and Infection

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JoVE Journal Immunology and Infection
Transfection efficace d’ARNm transcrit in vitro dans des cellules cultivées à l’aide de nanoparticules de peptide-poloxamine
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Transfection efficace d’ARNm transcrit in vitro dans des cellules cultivées à l’aide de nanoparticules de peptide-poloxamine

Article DOI: 10.3791/64288-v • 10:16 min • August 17th, 2022
August 17th, 2022 •
*1, *1, 1, 1, 1, 1, 1, 2, 1, 3, 1
1National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, Third Military Medical University, 2Department of Pediatrics, Ludwig-Maximilians University of Munich, 3Department of Pharmacy, Southwest Hospital, Third Military Medical University
* These authors contributed equally

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Une nanoparticule peptide-poloxamine auto-assemblée (PP-sNp) est développée à l’aide d’un dispositif de mélange microfluidique pour encapsuler et délivrer in vitro de l’ARN messager transcrit. L’ARNm/PP-sNp décrit pourrait transfecter efficacement des cellules cultivées in vitro.

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Immunologie et infection numéro 186 Livraison de gènes ARN messager transcrit in vitro systèmes d’administration poloxamine nanoparticule
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