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Journal / Immunology and Infection / 펩티드-폴록사민 나노입자를 사용하여 배양된 세포에서 시험관내 트랜스크립션된 mRNA의…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
펩티드-폴록사민 나노입자를 사용하여 배양된 세포에서 시험관내 트랜스크립션된 mRNA의 효율적인 형질감염
An In vitro Model to Study Heterogeneity of Human Macrophage Differentiation and Polarization
Journal (Immunology and Infection)
An In vitro Model to Study Heterogeneity of Human Macrophage Differentiation and Polarization
Single Cell Measurements of Vacuolar Rupture Caused by Intracellular Pathogens
Journal (Immunology and Infection)
Single Cell Measurements of Vacuolar Rupture Caused by Intracellular Pathogens
 
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펩티드-폴록사민 나노입자를 사용하여 배양된 세포에서 시험관내 트랜스크립션된 mRNA의 효율적인 형질감염

Article DOI: 10.3791/64288-v • 10:16 min • August 17th, 2022
August 17th, 2022 •
*1, *1, 1, 1, 1, 1, 1, 2, 1, 3, 1
1National Engineering Research Center of Immunological Products, Department of Microbiology and Biochemical Pharmacy, Third Military Medical University, 2Department of Pediatrics, Ludwig-Maximilians University of Munich, 3Department of Pharmacy, Southwest Hospital, Third Military Medical University
* These authors contributed equally

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자체 조립된 펩타이드-폴록사민 나노입자(PP-sNp)는 미세유체 혼합 장치를 사용하여 개발 되어 시험관 내 전사된 메신저 RNA를 캡슐화하고 전달합니다. 기술된 mRNA/PP-sNip는 배양된 세포를 시험관내에서 효율적으로 형질감염시킬 수 있었다.

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면역학 및 감염 문제 186 유전자 전달 시험관내 전사된 메신저 RNA 전달 시스템 폴록사민 나노입자
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