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Journal / Chemistry / 온테더 설포늄 중심을 사용한 순환 펩타이드…
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Chemistry

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JoVE Journal Chemistry
온테더 설포늄 중심을 사용한 순환 펩타이드 구성
An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry
Journal (Chemistry)
An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry
Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography
Journal (Chemistry)
Microfluidic Chips for In Situ Crystal X-ray Diffraction and In Situ Dynamic Light Scattering for Serial Crystallography
 
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온테더 설포늄 중심을 사용한 순환 펩타이드 구성

Article DOI: 10.3791/64289-v • 07:11 min • September 28th, 2022
September 28th, 2022 •
*1, *1,2, *1, 3, 1,2, 1, 3, 1,2, 1,2
1Pingshan Translational Medicine Center, Shenzhen Bay Laboratory, 2Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, 3Department of Radiation Oncology, the First Affiliated Hospital, Anhui Medical University
* These authors contributed equally

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Click here for the English version.

이 프로토콜은 시스테인과 메티오닌 사이의 비스알킬화와 프로파길 설포늄 중심에 의해 유발되는 용이한 티올-인 반응을 통한 고리형 펩타이드의 합성을 제시합니다.

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화학 이슈 187 고리형 펩타이드 비스알킬화/탈알킬화 프로파길 브로마이드 안정화 시스테인 메티오닌
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