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Chromatin Immunoprecipitation from Human Embryonic Stem Cells

Chromatin Immunoprecipitation from Human Embryonic Stem Cells

Article DOI: 10.3791/780-v 10:37 min July 22nd, 2008
July 22nd, 2008



The differentiation of ESC coincides with cell-type specific changes in the structure and composition of chromatin. The detection of those changes provides valuable insights into the mechanisms that define stemcellness and cell differentiation. Chromatin immunoprecipitation (ChIP) represents a valuable method to dissect the molecular mechanisms underlying stem cell differentiation.


Chromatin Immunoprecipitation Human Embryonic Stem Cells Stem Cells Self-renewal Multipotency Differentiation Transcription Factors Signaling Molecules Gene Expression Patterns Cell Differentiation Process Chromatin Structure Histones Epigenetic Factors Histone Variants Transcription Factors Chromatin Immunoprecipitation (ChIP)
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