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JoVE Journal
Biology

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Chromatin Immunoprecipitation from Human Embryonic Stem Cells
 

Chromatin Immunoprecipitation from Human Embryonic Stem Cells

Article doi: 10.3791/780
July 22nd, 2008 Usage Statistics

Summary July 22nd, 2008

The differentiation of ESC coincides with cell-type specific changes in the structure and composition of chromatin. The detection of those changes provides valuable insights into the mechanisms that define stemcellness and cell differentiation. Chromatin immunoprecipitation (ChIP) represents a valuable method to dissect the molecular mechanisms underlying stem cell differentiation.

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