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A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
A Method to Define the Effects of Environmental Enrichment on Colon Microbiome Biodiversity in a Mouse Colon Tumor Model
DOI:

08:14 min

February 28, 2018

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Chapters

  • 00:04Title
  • 00:50Environmentally Enriched Cage Set Up
  • 02:36Stool Collection at 16 Weeks of Age
  • 03:53Processing gDNA from the Stool
  • 06:00Results: The Effect of Enhanced Environments on Microbiome Biodiversity
  • 07:28Conclusion

Summary

Automatic Translation

Environmental Enrichment (EE) is an animal housing environment that is used to reveal mechanisms that underlie the connections between lifestyle, stress, and disease. This protocol describes a procedure that uses a mouse model of colon tumorigenesis and EE to specifically define alterations in microbiota biodiversity that may impact animal mortality.

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