Journal
/
/
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
JoVE Journal
Medicine
Author Produced
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
DOI:

08:34 min

November 18, 2018

, , , , ,

Chapters

  • 00:00Title
  • 01:20Pre-operative Preparation
  • 02:02Anaesthesia and Endotracheal Intubation
  • 03:11Preparation of the Surgical Site
  • 03:38Left Atrial Stenosis Surgery
  • 06:11Confirm the Success of Left Atrial Stenosis with Echocardiography
  • 06:21Representative Results
  • 07:43Conclusion

Summary

Automatic Translation

Left atrial stenosis (LAS) is a novel surgical technique used for studying group 2 pulmonary hypertension (PH) and mechanisms underlying pulmonary venous arterialization. Here, we present a protocol to constrict the left atrium using a titanium clip to cause pulmonary venous arterialization and moderate PH in a rat.

Related Videos

Read Article