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Journal / Developmental Biology / Modello di impatto corticale controllato di…
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Developmental Biology

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JoVE Journal Developmental Biology
Modello di impatto corticale controllato di lesioni cerebrali del topo con trapianto terapeutico di cellule neurali derivate da cellule staminali indotte dall'uomo
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Modello di impatto corticale controllato di lesioni cerebrali del topo con trapianto terapeutico di cellule neurali derivate da cellule staminali indotte dall'uomo

Article DOI: 10.3791/59561-v • 09:29 min • July 10th, 2019
July 10th, 2019 •
1,2, 1,2,3, 1,2,3
1Center for Neuroscience and Regenerative Medicine, Uniformed Services University, 2Department of Anatomy, Physiology, and Genetics, Uniformed Services University, 3Graduate Program in Neuroscience, Uniformed Services University

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Questo protocollo dimostra le metodologie per un modello murino di lesioni cerebrali traumatiche a cranio aperto e il trapianto di cellule derivate da cellule staminali pluripotenti indotte umane coltivate nel sito della lesione. Test comportamentali e istologici dei risultati di queste procedure sono descritti anche in breve.

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Biologia dello sviluppo numero 149 lesione cerebrale traumatica corteccia craniectomia sensomotorio trapianto cellule staminali
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