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方法Nanoformulated的抗逆转录病毒药物的血源性巨噬细胞运输的发展
JoVE Journal
Bioengineering
This content is Free Access.
JoVE Journal Bioengineering
Methods Development for Blood Borne Macrophage Carriage of Nanoformulated Antiretroviral Drugs
DOI:

18:46 min

December 09, 2010

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Chapters

  • 00:05Title
  • 03:21Manufacturing: Wet Milling nano-ART by NETZSCH MicroCer Methods
  • 06:44Manufacturing: Homogenizing nanoART by Avestin EmulsiFlex C5
  • 07:52Manufacturing: Sonication by Cole Parmer Ultrasonic Processor
  • 09:58NanoART Visualization and Morphology
  • 10:56Biology of nanaART
  • 15:37Representative Results
  • 17:21Conclusion

Summary

Automatic Translation

茚地那韦,利托那韦,依非韦伦和阿扎那韦的纳米颗粒制造,采用湿磨,同质化和超声。这些nanoformulations,统称nanoformulated抗逆转录病毒疗法(nanoART),评估巨噬细胞为基础的药物交付。单核细胞衍生的巨噬细胞nanoART摄取,保留和缓释进行了测定。这些初步的研究表明,nanoART临床使用的潜力。

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