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JoVE Journal
Bioengineering

This content is Open Access.

The Three-Dimensional Human Skin Reconstruct Model
 

The Three-Dimensional Human Skin Reconstruct Model: a Tool to Study Normal Skin and Melanoma Progression

Article doi: 10.3791/2937
August 3rd, 2011 Usage Statistics

Summary August 3rd, 2011

In this report, we describe the three-dimensional skin reconstruct model which mimics human skin in architecture and composition. Melanocyte physiology, melanoma progression and the fate of dermal stem cells have been investigated using the skin reconstruct model. The model is also useful as a preclinical tool for drug assessment.

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