Journal
/
/
在实验性自身免疫性脑脊髓炎(EAE)抗性品系小鼠继转移和抗原挑战克服反应迟钝
JoVE Journal
Immunology and Infection
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Immunology and Infection
Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis (EAE) Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge
DOI:

08:38 min

April 09, 2012

, ,

Chapters

  • 00:05Title
  • 01:28Preparing CFA-emulsified Antigen
  • 03:08Immunization of Donor Mice
  • 03:51Isolation of Lymph Node Cells after Immunization and Re-stimulation with Antigen
  • 06:07Harvest of Re-stimulated Lymph Node Cells and Adoptive Transfer
  • 06:47Antigenic Challenge of Recipient Mice and Development of Disease
  • 07:31Results: Kinetics of Disease Progression Following Immunization, Adoptive Transfer and Challenge
  • 07:58Conclusion

Summary

Automatic Translation

某些鼠标菌株能够抵抗与髓鞘碱性蛋白诱导实验性自身免疫性脑脊髓炎(EAE)。这里描述的是一个简单的免疫协议,扭转反应迟钝和麻痹性疾病引起几个典型的EAE的耐鼠标污渍。

Related Videos

Read Article