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JoVE Journal
Biology
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Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases
 

Use of a Robot for High-throughput Crystallization of Membrane Proteins in Lipidic Mesophases

Article DOI: 10.3791/4000
September 1st, 2012

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Summary September 1st, 2012

Herein is described a robotic approach to high-throughput crystallization of membrane proteins in lipidic mesophases for use in structure determination using macromolecular X-ray crystallography. Three robots capable of handling the viscous and sticky protein-laden mesophase integral to the method are introduced.

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