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在啮齿类动物的肠动力及胃肠壁的炎症分析功能评价一个标准化的模式肠道操作
JoVE Journal
Medicine
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JoVE Journal
Medicine
Functional Assessment of Intestinal Motility and Gut Wall Inflammation in Rodents: Analyses in a Standardized Model of Intestinal Manipulation
Please note that all translations are automatically generated.
Click here for the English version.
在啮齿类动物的肠动力及胃肠壁的炎症分析功能评价一个标准化的模式肠道操作
DOI:
10.3791/4086-v
•
09:44 min
•
September 11, 2012
•
Tim O. Vilz
,
Marcus Overhaus
,
Burkhard Stoffels
,
Martin von Websky
,
Joerg C. Kalff
,
Sven Wehner
1
Department of Surgery
,
University of Bonn
Chapters
00:05
Title
01:14
Operative Procedure and Postoperative Care
02:50
Functional Studies Twenty-Four Hours Post Intestinal Manipulation
04:32
Colon Transit Time
05:03
Histochemical Analysis and Organ Culture of Muscularis Externa
07:25
Representative Post Operative Ileus Results
09:15
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
术后肠梗阻(POI)是腹部外科手术的并发症导致的发病率和住院时间延长。由于缺乏预防或治疗策略加强研究是必要的。因此,我们建立了一个标准化的和可行的小鼠模型的病理生理POI调查和研究潜在的治疗方案。
Tags
Functional Assessment
Intestinal Motility
Gut Wall Inflammation
Rodents
Standardized Model
Intestinal Manipulation
Gastrointestinal Tract
Human Diseases
Animal Research Models
Cellular And Molecular
Intestinal Pathology
Tunica Mucosa
Muscularis Externa
Immunocompetent Organ
Resident Immunocytes
Inflammation Of The Bowel Wall
Postoperative Ileus
Abdominal Surgery
Proinflammatory Mediators
IL-6
IL-1β
Nitric Oxide (NO)
Immunocytes Extravasate
Polymorphonuclear Neutrophils (PMN)
Monocytes
Intestinal Paralysis
Increased Risk Of Aspiration
Bacterial Translocation
Infectious Complications
Sepsis
Multi Organ Failure
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