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JoVE Journal
Biology

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Orthotopic Mouse Model of Colorectal Cancer
 

Orthotopic Mouse Model of Colorectal Cancer

Article DOI: 10.3791/484
December 4th, 2007

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Summary December 4th, 2007

Two techniques can be used to establish this model: injection of a cancer cell suspension into the cecal wall or transplantation of a piece of subcutaneous tumor onto the cecum. This model is useful for studying the natural progression of colorectal cancer and testing new therapeutic agents against colorectal cancer.

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