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2-oclusão do vaso / hipotensão
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2-oclusão do vaso / hipotensão: um modelo de rato de isquemia cerebral

Article DOI: 10.3791/50173
June 22nd, 2013 •
1,2,3, 2,3
1Department of Emergency Medicine, Wayne State University School of Medicine, 2Cardiovascular Research Institute, Wayne State University School of Medicine, 3Department of Physiology, Wayne State University School of Medicine

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June 22nd, 2013

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Oclusão carotídea bilateral juntamente com hipotensão sistêmica produz isquemia cerebral em ratos, resultando em danos ao hipocampo com gravidade reproduzível. Assuntos animais são prejudicados com padrões previsíveis de danos cerebrais, eles se recuperam expediente, e as taxas de mortalidade são comparativamente baixas.

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