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Anvendelse af<em> In vivo</em> Imaging til Monitor Progression of Experimental Mouse Cytomegalovirusinfektion i Nyfødte
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Immunology and Infection
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JoVE Journal Immunology and Infection
Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Anvendelse af<em> In vivo</em> Imaging til Monitor Progression of Experimental Mouse Cytomegalovirusinfektion i Nyfødte

DOI:
10.3791/50409-v

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05:53 min

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July 06, 2013

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, , ,
1ImmunoRhumatologie Moléculaire, INSERM UMR_S 1109, Centre de Recherche d’Immunologie et d’Hématologie,Université de Strasbourg

Chapters

  • 00:05Title
  • 01:16Preparation of Viral Suspension
  • 02:14Injection of Neonates
  • 03:25In vivo Imaging
  • 05:00Results: Viral Expression Over Time
  • 05:32Conclusion

Summary

Automatic Translation

Automatic Translation

Human cytomegalovirus (HCMV) infektion i nyfødte udgør en vigtig årsag til mental retardering, men de molekylære begivenheder, der førte til virus-induceret patogenese stadig dårligt forstået. For at undersøge dynamikken i hjernen infektion, vi tilpasset hel-dyr<em> In vivo</em> Imaging at udføre tidsforløb analyse af nyfødte er smittet med en luciferase-rekombinant virus.

Tags

In Vivo ImagingMouse CytomegalovirusMCMVNeonatal InfectionCentral Nervous SystemCNSViral DisseminationLuciferase ReporterTime-course Analysis

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