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基因编码的分子探针来研究G蛋白偶联受体
 
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基因编码的分子探针来研究G蛋白偶联受体

Article doi: 10.3791/50588
September 13th, 2013

Summary September 13th, 2013

Please note that all translations are automatically generated.

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在GPCR的各种目标的位置,我们基因编码的非天然氨基酸,对 - 叠氮基-L-苯丙氨酸,并显示在叠氮基团中的不同的应用程序的通用性。这些包括有针对性的光交联技术,以确定在一个G蛋白偶联受体的配体结合口袋的残基,和位点特异性生物正交的GPCR与肽表位标签或荧光探针的修饰。

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