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胫骨神经切断术 - 一个标准化的模型失神经诱导小鼠骨骼肌
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JoVE Journal Medicine
Tibial Nerve Transection – A Standardized Model for Denervation-induced Skeletal Muscle Atrophy in Mice
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胫骨神经切断术 - 一个标准化的模型失神经诱导小鼠骨骼肌

DOI:
10.3791/50657-v

•

10:50 min

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November 03, 2013

•

,
1Keenan Research Centre of the LiKaShing Knowledge Institute,St Michaels Hospital, 2Department of Surgery,McMaster University

Chapters

  • 00:05Title
  • 01:31Surgical Procedure
  • 05:03Post Operative Care
  • 06:13Denervated Gastrocnemius and Soleus Muscle Harvest
  • 09:24Results: Muscle Atrophy in Denervated Mice
  • 10:21Conclusion

Summary

Automatic Translation

Automatic Translation

胫神经横断模型骨骼肌萎缩是一种耐受性良好，验证和可重复的模型。中描述和演示C57Black6小鼠模型手术协议。

Tags

Tibial Nerve TransectionDenervation-induced Skeletal Muscle AtrophyRodent ModelGastrocnemius MuscleMuscle Fiber TypeC57Black6 Mouse

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