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Medicine
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脑Microslices的兴奋性刺激作为<em>在体外</em>中风模型
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Medicine
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JoVE Journal
Medicine
Excitotoxic Stimulation of Brain Microslices as an
In vitro
Model of Stroke
Please note that all translations are automatically generated.
Click here for the English version.
脑Microslices的兴奋性刺激作为<em>在体外</em>中风模型
DOI:
10.3791/51291-v
•
07:00 min
•
February 04, 2014
•
Kathryn A. Skelding
,
Jacinta M. Arellano
,
David A. Powis
,
John A. Rostas
1
School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute
,
The University of Newcastle
,
2
School of Health and Human Sciences
,
Southern Cross University
,
3
School of Medicine and Public Health
,
The University of Newcastle
Chapters
00:05
Title
01:08
Preparation of Microslices
02:27
Equilibration of Microslices
03:46
Excitotoxic Stimulation
05:26
Results: Viability of Microslices
06:41
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
我们已开发了可用于检查涉及兴奋性毒性介导的脑损伤的分子机制的脑切片的模型。这种技术产生可行的成熟的脑组织,并减少所需的实验动物数量,同时保持神经回路,细胞相互作用,和突触后车厢部分完好无损。
Tags
Brain Microslices
In Vitro Model
Stroke
Excitotoxicity
Neuropathology
Ischemic Stroke
Cell Culture
Molecular Pathways
Brain Regions
Excitotoxic Stimulation
Inhibitors
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