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DNBS / TNBS Colitis modellen: Inzicht geven Into Inflammatory Bowel Disease en effecten van vet in de voeding
JoVE Journal
Medicine
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JoVE Journal Medicine
DNBS/TNBS Colitis Models: Providing Insights Into Inflammatory Bowel Disease and Effects of Dietary Fat
DOI:

09:04 min

February 27, 2014

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Chapters

  • 00:05Title
  • 01:24Intra Rectal Dinitrobenzene Sulfonic Acid (DNBS) Administration
  • 02:52Collecting Tissues and Assessing Histological Damage in DNBS Challenged Mice
  • 04:27Myeloperoxidase (MPO) Assay of DNBS Challenged Intestinal Tissue
  • 05:25Results: Representative Effects of Dietary Oils on DNBS Colitis Severity of DNBS Challenged Intestinal Tissue
  • 08:18Conclusion

Summary

Automatic Translation

DNBS / TNBS colitis biedt een alternatieve en goedkope methode om de pathobiology van ontstekingsdarmziekte bestuderen. Het protocol besproken in dit document schetst de succesvolle toepassing van DNBS om colitis te induceren bij muizen en ratten en maakt het mogelijk om grondig te bestuderen host-mediated intestinale reacties.

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