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Neuroscience

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JoVE Journal Neuroscience
Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex
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Live Imaging of Mitosis in the Developing Mouse Embryonic Cortex

Article DOI: 10.3791/51298
June 4th, 2014 •
1, 1,2
1Department of Molecular Genetics and Microbiology, Duke University Medical Center, 2Departments of Neurobiology and Cell Biology, Duke Institute for Brain Sciences, Duke University Medical Center

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Summary
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June 4th, 2014

Neural progenitor mitosis is a critical parameter of neurogenesis. Much of our understanding of neural progenitor mitosis is based on analysis of fixed tissue. Live imaging in embryonic brain slices is a versatile technique to assess mitosis with high temporal and spatial resolution in a controlled environment.

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