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Journal / Biology / Glycopeptide Capture for Cell Surface Proteomics
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Glycopeptide Capture for Cell Surface Proteomics
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Glycopeptide Capture for Cell Surface Proteomics

Article DOI: 10.3791/51349 • 10:11 min • May 9th, 2014
May 9th, 2014 •
1, 1
1Department of Chemistry, Simon Fraser University

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Summary
Automatic Translation

Cell surface proteins are biologically important and widely glycosylated. We introduce here a glycopeptide-capture approach to solubilize, enrich, and deglycosylate these proteins for facile LC-MS based proteomic analyses.

Tags

Glycopeptide Capture Cell Surface Proteomics Extracellular Matrix Proteins Biomarker Discovery Cell-type Identification Drug-target Selection Glycosylation High-throughput Glycopeptide-capture Approach N-glycoproteomics LC-MS Protein Identity Protein Quantity Glycosylation Sites Cancer Research Stem Cell Research Drug Toxicity
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