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JoVE Journal
Immunology and Infection

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Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection
 

Analysis of the Epithelial Damage Produced by Entamoeba histolytica Infection

Article doi: 10.3791/51668
June 12th, 2014

Summary June 12th, 2014

Human infection by Entamoeba histolytica leads to amoebiasis, a major cause of diarrhea in tropical countries. Infection is initiated by pathogen interactions with intestinal epithelial cells, provoking the opening of cell-cell contacts and consequently diarrhea, sometimes followed by liver infection. This article provides a model to assess the early host-pathogen interactions to improve our understanding of amoebiasis pathogenesis.

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