Modelado astrocitoma Patogénesis<em> In Vitro</em> Y<em> En Vivo</em> Uso cortical astrocitos o células troncales nerviosas de ratones condicionales, Genéticamente Manipulados
Phenotypically wild-type astrocytes and neural stem cells harvested from mice engineered with floxed, conditional oncogenic alleles and transformed via viral Cre-mediated recombination can be used to model astrocytoma pathogenesis in vitro and in vivo by orthotopic injection of transformed cells into brains of syngeneic, immune-competent littermates.