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The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures
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The Analysis of Neurovascular Remodeling in Entorhino-hippocampal Organotypic Slice Cultures

Article DOI: 10.3791/52023-v • 08:27 min • October 23rd, 2014
October 23rd, 2014 •
1, 2, 1
1Anatomical Institute, Department of Biomedicine Basel, University of Basel, 2Department of Neonatology, University Children's Hospital (UKBB), University of Basel

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A protocol for entorhino-hippocampal organotypic slice cultures, which allows reproducing many aspects of ischemic brain injury, is presented. By studying changes of the neurovasculature in addition to changes in the neurons, this protocol is a versatile tool to study plastic changes in neural tissue after injury.

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Neurovascular Remodeling Entorhino-hippocampal Organotypic Slice Cultures Ischemic Brain Injury Neuronal Injury Secondary Death Oxygen And Glucose Deprivation (OGD) In Vitro Models Brain Blood Vessels Neural Tissue Hypoxia Organotypic Slice Culture Approach Vasculature Analysis
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