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A “Patient-Like” Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
JoVE Journal
Medicine
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JoVE Journal Medicine
A “Patient-Like” Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
DOI:

05:06 min

October 24, 2015

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Chapters

  • 00:05Title
  • 01:12Orthotopic Hepatocyte Implantation
  • 03:45Results: Gross Examination of Primary Hepatocellular Carcinoma and Metastasis
  • 04:41Conclusion

Summary

Automatic Translation

The metastatic spread of cancer is the major cause of cancer-related deaths. We provide an in-depth description of our survival surgery methodology for establishing a “patient-like” orthotopic syngeneic mouse model system for studying the mechanisms of metastasis in solid organ tumors.

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