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Nyreskade Mikroinjeksjon i Sebrafisk til Model Akutt nyreskade
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Nyreskade Mikroinjeksjon i Sebrafisk til Model Akutt nyreskade

Article DOI: 10.3791/54241-v • 07:58 min • July 17th, 2016
July 17th, 2016 •
1,2, 1,2
1Center for Zebrafish Research, Department of Biological Sciences, University of Notre Dame, 2Center for Stem Cells and Regenerative Medicine, Department of Biological Sciences, University of Notre Dame

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Nyreskader pådratt fra nephrotoxins, som inkluderer legemidler som spenner fra antibiotika til kjemoterapeutika, kan resultere i komplekse lidelser som patogenesen er fortsatt ufullstendig forstått. Denne protokollen viser hvordan sebrafisk kan anvendes for sykdom modellering av disse forhold, som kan brukes til identifisering av renoprotective tiltak.

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Medisin sebrafisk nyre nyreskade renal clearance akutt nyreskade mikroinjeksjon gentamicin
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