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Urinvejsinfektion i en lille dyremodel: transuretral kateterisation af mandlige og kvindelige mus
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Urinary Tract Infection in a Small Animal Model: Transurethral Catheterization of Male and Female Mice
DOI:

10:23 min

December 01, 2017

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Chapters

  • 00:05Title
  • 00:47Preparation of Catheters and Uropathogenic E. coli for Infection
  • 02:08Transurethral Instillation of Female Mice
  • 03:43Transurethral Instillation of Male Mice
  • 04:56Determination of CFU in Infected Organs
  • 06:09Flow Cytometric Analysis of Bladder Tissue
  • 08:31Results: Transurethral Catheterization to Induce Urinary Tract Infections
  • 09:57Conclusion

Summary

Automatic Translation

Den etablerede model af transuretral kateterisation af mus giver mulighed for undersøgelse af blæren patologier, herunder urinvejsinfektion, men kan kun udføres i hunner. En ny model for mandlige transuretral instillation, præsenteres her, vil gøre forskning i et område præget af stærk kliniske og epidemiologiske forskelle mellem kønnene.

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