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流感病毒在小鼠感染模型中的研究
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Influenza A Virus Studies in a Mouse Model of Infection
DOI:

10:44 min

September 07, 2017

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Chapters

  • 00:05Title
  • 01:05Intranasal Infection
  • 01:49Characterization of Viral Pathogenesis
  • 05:29Homogenization of Lungs and Nasal Mucosa and Virus Tritation by Indirect Immunofluorescence
  • 08:30Results: Viral Pathogenesis and Humoral Responses in Influenza A Virus Infected Mice
  • 10:03Conclusion

Summary

Automatic Translation

甲型流感病毒 (IAVs) 是人类重要的呼吸道病原体。为了了解 IAVs 的致病性和对新疫苗方法进行临床前测试, 需要模仿人体生理学的动物模型。在这里, 我们描述的技术, 以评估 IAV 病机, 体液反应和疫苗的效果使用小鼠感染模型。

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