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血管性血友病因子-血小板串形成的流室模型研究血管血友病因子的病理生理学
JoVE Journal
Medicine
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JoVE Journal
Medicine
Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
Please note that all translations are automatically generated.
Click here for the English version.
血管性血友病因子-血小板串形成的流室模型研究血管血友病因子的病理生理学
DOI:
10.3791/55917-v
•
08:30 min
•
August 14, 2017
•
Alison Michels
,
Laura L. Swystun
,
Jeffrey Mewburn
,
Silvia Albánez
,
David Lillicrap
1
Department of Pathology and Molecular Medicine
,
Queen’s University
,
2
Department of Medicine
,
Queen’s University
Chapters
00:05
Title
01:02
Endothelial Cell Flow Chamber Seeding
02:26
Flow Apparatus Assembly and Miroscope Setup
04:15
von Willebrand Factor (VWF)-Platelet String Formation and Quantification
07:05
Results: Histones Mediate VWF-Platelet String Formation
07:43
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
本文介绍了一种方法来评估内皮血管性血友病因子释放和随后的血小板捕获在流体剪切应激反应的炎症刺激使用的
体外
流室系统。
Tags
Von Willebrand Factor
VWF-platelet String Formation
Flow Chamber Model
Collagen
Endothelial Cells
Platelets
Secretagogues
In Vitro
Microscopy
Syringe Pump
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