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Undersøge von Willebrands faktor Patofysiologi bruger en Flow kammer Model af von Willebrand faktor-trombocyttal streng dannelse
JoVE Journal
Medicine
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JoVE Journal Medicine
Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
DOI:

08:30 min

August 14, 2017

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Chapters

  • 00:05Title
  • 01:02Endothelial Cell Flow Chamber Seeding
  • 02:26Flow Apparatus Assembly and Miroscope Setup
  • 04:15von Willebrand Factor (VWF)-Platelet String Formation and Quantification
  • 07:05Results: Histones Mediate VWF-Platelet String Formation
  • 07:43Conclusion

Summary

Automatic Translation

I dette papir, vi beskriver en metode til at vurdere endotel von Willebrands faktor frigivelse og den efterfølgende trombocyt fange under væske shear stress reaktion på inflammatoriske stimuli ved hjælp af en in vitro- flow kammer system.

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