Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Cancer Research

This content is Open Access.

Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells
 

Application of Laser Micro-irradiation for Examination of Single and Double Strand Break Repair in Mammalian Cells

Article doi: 10.3791/56265
September 5th, 2017

Summary September 5th, 2017

Confocal fluorescence microscopy and laser micro-irradiation offer tools for inducing DNA damage and monitoring the response of DNA repair proteins in selected sub-nuclear areas. This technique has significantly advanced our knowledge of damage detection, signaling, and recruitment. This manuscript demonstrates these technologies to examine single and double strand break repair.

Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
simple hit counter