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Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures
JoVE Journal
Medicine
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JoVE Journal Medicine
Improvement of a Closed Chest Porcine Myocardial Infarction Model by Standardization of Tissue and Blood Sampling Procedures
DOI:

10:01 min

March 12, 2018

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Chapters

  • 00:04Title
  • 00:43Anesthesia and Preparation of the Animal
  • 06:07Sampling the Heart
  • 08:05Results: Treatment with FXIIa Inhibitor
  • 09:05Conclusion

Summary

Automatic Translation

Here we demonstrate a protocol to standardize sampling procedures of an established porcine model of acute myocardial infarction in order to increase its translational value in the understanding of the pathophysiology of myocardial ischemia/reperfusion injury and to test novel drug candidates.

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