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Terapi test i en klumpformet-baseret 3D celle kultur Model for hoved og hals planocellulært karcinom
JoVE Journal
Cancer Research
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JoVE Journal Cancer Research
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
DOI:

06:11 min

April 20, 2018

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Chapters

  • 00:05Title
  • 00:45Processing the Tumor Specimen
  • 01:39Seeding the Cells on Ultra-low Adhesion Cell Culture Plates and Exposing Spheroids to Multimodal Standard or Experimental Tumor Therapy
  • 02:52Assessment of Spheroid Size and Extent of Cellular Proliferation for Assay Read-out
  • 04:08Results: Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
  • 05:12Conclusion

Summary

Automatic Translation

Vi beskriver udviklingen i en klumpformet-baseret, tre-dimensionelle in vitro- model, der gør det muligt for os at teste den nuværende standard for eksperimentel behandling regimer for hoved og hals planocellulært karcinom i cellelinjer, med henblik på at evaluere terapi modtagelighed og modstand på primærelementer fra humant prøvemateriale i fremtiden.

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