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Terapi test i en klumpformet-baseret 3D celle kultur Model for hoved og hals planocellulært karcinom
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1Department of Otorhinolaryngology,Johannes-Gutenberg University Medical Center, 2Department of Otorhinolaryngology,Technical University of Munich Medical Center, 3Department of Otorhinolaryngology,Ludwig-Maximilian-University Medical Center, 4Department of Otorhinolaryngology,University of Goettingen Medical Center
Chapters
- 00:05Title
- 00:45Processing the Tumor Specimen
- 01:39Seeding the Cells on Ultra-low Adhesion Cell Culture Plates and Exposing Spheroids to Multimodal Standard or Experimental Tumor Therapy
- 02:52Assessment of Spheroid Size and Extent of Cellular Proliferation for Assay Read-out
- 04:08Results: Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
- 05:12Conclusion
Vi beskriver udviklingen i en klumpformet-baseret, tre-dimensionelle in vitro- model, der gør det muligt for os at teste den nuværende standard for eksperimentel behandling regimer for hoved og hals planocellulært karcinom i cellelinjer, med henblik på at evaluere terapi modtagelighed og modstand på primærelementer fra humant prøvemateriale i fremtiden.
