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Nasal potentielle forskel at kvantificere Trans-epitelial Ion Transport i mus
JoVE Journal
Biology
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JoVE Journal Biology
Nasal Potential Difference to Quantify Trans-epithelial Ion Transport in Mice
DOI:

08:55 min

July 04, 2018

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Chapters

  • 00:04Title
  • 00:49Pre-test Assessment and Management
  • 01:59Assessment and Management During the Test
  • 06:55Results: Representative Nasal PD Tracings
  • 08:03Conclusion

Summary

Automatic Translation

Vi præsenterer her, en protokol for at måle nasal spændingsforskel i mus. Testen kvantificerer funktion af transmembrane ion transportvirksomheder som cystisk fibrose transmembrane ledningsevne regulator og epitelial natrium-kanal. Det er værdifuldt at evaluere effekten af nye terapier for cystisk fibrose.

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