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JoVE Journal
Biochemistry

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A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton
 

A Direct Force Probe for Measuring Mechanical Integration Between the Nucleus and the Cytoskeleton

Article DOI: 10.3791/58038
July 29th, 2018

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Summary July 29th, 2018

In this protocol, we describe a micropipette method to directly apply a controlled force to the nucleus in a living cell. This assay allows interrogation of nuclear mechanical properties in the living, adherent cell.

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