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12-Dithiolane 改性自组装肽的合成与表征
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JoVE Journal
Chemistry
Synthesis and Characterization of 1,2-Dithiolane Modified Self-Assembling Peptides
Please note that all translations are automatically generated.
Click here for the English version.
12-Dithiolane 改性自组装肽的合成与表征
DOI:
10.3791/58135-v
•
09:54 min
•
August 20, 2018
•
Ruben Neves
,
Kailyn Stephens
,
Jillian E. Smith-Carpenter
1
Department of Chemistry and Biochemistry
,
Fairfield University
Chapters
00:04
Title
00:42
1,2-Dithiolane Modified Peptide Synthesis and Purification
02:51
Solid-Phase Peptide Synthesis (SPPS) and On-Resin Dithiolane Precursor Coupling and Thioacetate Deprotection and Peptide-Resin Cleavage
04:57
1,2-Dithiolane Modified Peptide Purification and Amyloid Fiber Formation
06:31
Spectroscopic Amyloid Fiber Characterization and Amyloid Fiber Microscopy
08:13
Results: 1,2-Dithiolane Modified Peptide Supramolecular Characterization
09:23
Conclusion
Summary
Automatic Translation
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Automatic Translation
一种合成 12-dithiolane 修饰肽的协议, 以及肽自组装产生的超分子结构的表征。
Tags
1
2-dithiolane
Self-assembling Peptides
Supermolecular Structures
Peptide Synthesis
Organic Synthesis
Characterization
Reaction Monitoring
Thin-layer Chromatography
Extraction
Coupling Reaction
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