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치료 약물은 중요 한 질병에 항생제의 동위 원소 희석 HPLC-MS/MS에 의해 Monitoring 다중화
JoVE Journal
Medicine
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JoVE Journal Medicine
Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
DOI:

11:17 min

August 30, 2018

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Chapters

  • 00:04Title
  • 01:05Preparation of the Calibrators, Quality Control Samples, and Internal Standards Mix
  • 02:29Buffer Preparation for Chromatography
  • 03:47Sample Cleanup and HPLC-MS/MS Analysis
  • 06:28Quality Assessment and Quantification
  • 08:14Results: Data Analysis and Quantification of Piperacillin
  • 09:44Conclusion

Summary

Automatic Translation

여기 선물이 집중 치료 단위, 즉 cefepime, meropenem, ciprofloxacin, moxifloxacin, linezolid, 및 piperacillin에서에서 자주 사용 되는 항생제의 정량화를 위한 탠덤 질량 분석 기반 프로토콜.

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