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Chapters
- 00:04Title
- 00:51Glycyrrhizae Radix et Rhizome (GR) Methanol Extract (GRex) Preparation
- 02:05Mouse Middle Cerebral Artery Occlusion (MCAO) Model
- 04:10Measurement of Volume of Damaged Brain Tissue
- 05:02Hematoxylin and Eosin (H&E) and Cresyl Violet Staining
- 07:18Results: Representative GRex Treatment Effects on MCAO-Injured Mice
- 08:24Conclusion
I denne undersøgelse ændre vi en eksisterende Eksperimentel metode til at opnå mere reproducerbare resultater, ved at etablere en midterste cerebral arterie okklusion (MCAO) musemodel. Oral administration af Glycyrrhizae Radix et rhizom (GR) methanol ekstrakt (GRex), efter slagtilfælde induktion, faldt betydeligt samlede infarkt volumen i forhold til den ubehandlede kontrolgruppe.
Tags
NeuroprotectiveGlycyrrhizae Radix Et RhizomaTransient Middle Cerebral Artery OcclusionMouse ModelNatural CompoundsIschemic TimingMiddle Cerebellar ArteryGlycyrrhizae Radix Et Rhizome ExtractMethanol ExtractionFreeze-dryingDimethylsulfoxideC57BL/6 MouseCommon Carotid ArteryExternal Carotid ArteryInternal Carotid ArterySilicone-coated Monofilament
