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1Department of Pharmacology and Toxicology,The University of Mississippi Medical Center, 2Department of Medicine, Division of Nephrology,Rush University Medical Center, 3Department of Medicine, Division of Nephrology,The University of Mississippi Medical Center, 4Department of Neurology,The University of Mississippi Medical Center
Chapters
- 00:04Title
- 01:34Kidney Isolation
- 02:33Kidney Homogenization, Incubation, and Straining
- 05:10Glomeruli Enumeration and Nephron Number Extrapolation
- 06:20Results: Representative Nephron Quantification
- 07:11Conclusion
As estimativas do número inteiro do nephron do rim são importantes clìnica e experimentalmente, porque há uma associação inversa entre o número do nephron e um risco aumentado de doença renal e cardiovascular. Nisto, o uso do método ácido da maceração, que fornece estimativas rápidas e de confiança do número inteiro do nephron do rim, é demonstrado.
