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JoVE Journal
Bioengineering

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Detection of Endotoxin in Nano-formulations Using Limulus Amoebocyte Lysate (LAL) Assays
 
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Detection of Endotoxin in Nano-formulations Using Limulus Amoebocyte Lysate (LAL) Assays

Article doi: 10.3791/58830
January 30th, 2019

Summary January 30th, 2019

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Detection of endotoxins in engineered nanomaterials represents one of the grand challenges in the field of nanomedicine. Here, we present a case study that describes the framework composed of three different LAL formats to estimate potential endotoxin contamination in nanoparticles.

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