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一种可靠、可重复的可重复的大鼠部分股骨缺陷模型
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
A Reliable and Reproducible Critical-Sized Segmental Femoral Defect Model in Rats Stabilized with a Custom External Fixator
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一种可靠、可重复的可重复的大鼠部分股骨缺陷模型

DOI:
10.3791/59206-v

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08:20 min

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March 24, 2019

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, , , , , , ,
1Department of Orthopedics and Rehabilitation,University of Wisconsin-Madison, 2Department of Biomedical Engineering,University of Wisconsin-Madison, 3Summit Orthopedics

Chapters

  • 00:04Title
  • 00:58Bone Morphogenetic Protein-2 (rhBMP-2)-Soaked Sponge Scaffold and Surgical Preparation
  • 01:54Segmental Femoral Defect Induction
  • 05:50Results: Representative Segmental Femoral Defect Bone Recovery Analyses
  • 07:21Conclusion

Summary

Automatic Translation

Automatic Translation

在体内, 哺乳动物的临界骨缺损模型是必不可少的研究愈合机制和骨科治疗。在这里, 我们介绍了一种方案, 以创建可重复的, 节段, 股骨缺损在大鼠稳定使用外固定。

Tags

Segmental Femoral DefectRat ModelExternal FixatorBone RegenerationBone Morphogenetic ProteinSurgical ProtocolCritical-sized DefectDiaphyseal DefectLongitudinal Healing Studies

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