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Journal
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Cancer Research
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在微RNA的Vivo抑制下,降低小鼠的肿瘤生长
JoVE Journal
Cancer Research
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JoVE Journal
Cancer Research
In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
Please note that all translations are automatically generated.
Click here for the English version.
在微RNA的Vivo抑制下,降低小鼠的肿瘤生长
DOI:
10.3791/59322-v
•
00:07 min
•
August 23, 2019
•
Julia Ramirez-Moya
2
,
León Wert-Lamas
,
Adrián Acuña-Ruiz
2
,
Miguel A. Zaballos
2
,
Pilar Santisteban
2
1
Instituto de Investigaciones Biomédicas, CSIC-UAM
,
2
Ciberonc
,
Instituto de Salud Carlos III
Chapters
00:04
Title
00:49
Flank Inoculation and Intratumoral AntagomiR Treatment
02:23
Tumor Growth Analysis
03:10
Thyroid Orthotopic Inoculation and Systemic AntagomiR Treatment
05:05
Results: Representative Effects of In Vivo MicroRNA Inhibition on Tumor Growth in Mice
06:42
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
该协议将人类甲状腺肿瘤的异种移植和正交小鼠模型描述为测试基于微RNA的抑制剂治疗的平台。该方法是研究非编码RNA的功能及其作为新的治疗靶点的潜力的理想选择。
Tags
MicroRNA Inhibitor
Thyroid Cancer
Orthotopic Model
In Vivo Inhibition
Tumor Growth
Bioluminescence Imaging
AntagomiR
CAL-62 Cell Line
Immunodeficient Mice
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