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Journal
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Cancer Research
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高分解能共焦点顕微鏡による3D腫瘍スフェロイド侵入に対する移動性阻害剤の効果の特徴
JoVE Journal
Cancer Research
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JoVE Journal
Cancer Research
Characterization of the Effects of Migrastatic Inhibitors on 3D Tumor Spheroid Invasion by High-resolution Confocal Microscopy
Please note that all translations are automatically generated.
Click here for the English version.
高分解能共焦点顕微鏡による3D腫瘍スフェロイド侵入に対する移動性阻害剤の効果の特徴
DOI:
10.3791/60273-v
•
09:17 min
•
September 16, 2019
•
Jane Harmer
,
Nina Struve
,
Anke Brüning-Richardson
1
School of Applied Sciences
,
University of Huddersfield
,
2
Laboratory of Radiotherapy and Experimental Radiation Oncology, Humbertus Wald Tumorzentrum
,
University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf
Chapters
00:04
Title
01:01
Generation of Cell Spheroids
02:15
Collagen Invasion Assay
04:15
Preparation of Collagen Embedded Spheroids and Migratory Cells for Confocal Microscopy
07:13
Results: Cell Migration and Invasion
08:20
Conclusion
Summary
Automatic Translation
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Automatic Translation
ヒストンデアセチラーゼ(HDAC)阻害剤を用いた三次元(3D)侵入アッセイにおけるグリオーマ癌細胞移動に対する移行抑制剤の効果は、高分解能共焦点顕微鏡によって特徴付けられる。
Tags
3D Tumor Spheroid
Migrastatic Inhibitors
Confocal Microscopy
Cancer Research
Cytotoxic Drugs
Cell Migration
Cell Proliferation
3D Cell Culture
Glioma
Collagen
Cell Invasion
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