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Bioengineering
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用于表征用于超声触发药物释放的荧光标记微气泡的多时间尺度显微镜方法
JoVE Journal
Bioengineering
This content is Free Access.
JoVE Journal
Bioengineering
Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
Please note that all translations are automatically generated.
Click here for the English version.
用于表征用于超声触发药物释放的荧光标记微气泡的多时间尺度显微镜方法
DOI:
10.3791/62251-v
•
06:02 min
•
June 12, 2021
•
Charlotte Nawijn
,
Tim Segers
2
,
Guillaume Lajoinie
,
Ýrr Mørch
,
Sigrid Berg
5,6
,
Sofie Snipstad
6,7
,
Catharina de Lange Davies
,
Michel Versluis
1
Physics of Fluids group, Department of Science and Technology, MESA+ Institute for Nanotechnology and Technical Medical (TechMed) Center
,
University of Twente
,
2
BIOS Lab-on-a-Chip group, Max Planck Center Twente for Complex Fluid Dynamics, MESA+ Institute for Nanotechnology and Technical Medical (TechMed) Center
,
University of Twente
,
3
Department of Biotechnology and Nanomedicine
,
SINTEF Industry
,
4
Department of Circulation and Medical Imaging
,
Norwegian University of Science and Technology
,
5
Department of Health Research
,
SINTEF Digital
,
6
Cancer Clinic
,
St. Olav’s Hospital
,
7
Department of Physics
,
Norwegian University of Science and Technology
Chapters
00:05
Introduction
00:45
Imaging by Brightfield Microscopy
02:05
Imaging by Fluorescence Microscopy
02:52
Imaging Protocol by Intravital Microscopy
04:07
Results: In Vitro and In Vivo Behavior of Insonified Microbubble
05:22
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
所提出的方案可用于表征为超声触发的药物递送应用而设计的荧光标记微气泡的反应,包括其激活机制及其生物效应。本文涵盖了一系列
用于
捕获相关长度和时间尺度的
体外和体内
显微镜技术。
Tags
Microbubbles
Ultrasound
Drug Delivery
Fluorescence Microscopy
Brightfield Microscopy
Multi-timescale
Characterization
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