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DNA张力探针用于绘制免疫细胞的瞬时皮牛顿受体力
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
DNA Tension Probes to Map the Transient Piconewton Receptor Forces by Immune Cells
DOI:

06:53 min

March 20, 2021

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Chapters

  • 00:04Introduction
  • 00:41Surface Preparation and Activation of the Coverslip
  • 04:37Imaging Cell Receptor Forces
  • 05:21Results: Estimation of Quality and Functionalization of the DNA Probe Surface
  • 06:17Conclusion

Summary

Automatic Translation

本文描述了使用基于DNA的张力探针对免疫细胞施加的受体力进行成像的详细方案。这种方法可以实时映射受体力>4.7pN,并且可以随着时间的推移积分力。

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