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In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility
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JoVE Journal Neuroscience
In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

In Vivo Vascular Injury Readouts in Mouse Retina to Promote Reproducibility

DOI:
10.3791/63782-v

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07:35 min

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April 21, 2022

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, , , ,
1Department of Pathology & Cell Biology; Vagelos College of Physicians and Surgeons,Columbia University, 2Department of Molecular Pharmacology and Therapeutics; Vagelos College of Physicians and Surgeons,Columbia University, 3Department of Neurology; Vagelos College of Physicians and Surgeons,Columbia University, 4The Taub Institute for Research on Alzheimer’s Disease and the Aging Brain; Vagelos College of Physicians and Surgeons,Columbia University

Chapters

  • 00:04Introduction
  • 00:44OCT and Fluorescein Imaging
  • 02:08Fluorescein Image Processing
  • 03:26Retinal Layer Thickness
  • 04:01Disorganization of Retinal Inner Layers
  • 05:02Results: Quantification of FA and OCT Images in the Study of Retinal Vein Occlusion
  • 06:46Conclusion

Summary

Automatic Translation

Automatic Translation

Here, we present three data analysis protocols for fluorescein angiography (FA) and optical coherence tomography (OCT) images in the study of Retinal Vein Occlusion (RVO).

Tags

Keywords: Retinal ImagingVascular InjuryMouse ModelOptical Coherence TomographyFluorescein LeakageRetinal Layer Analysis

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