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一个线虫多巴胺神经元退化含量的应用验证潜在的帕金森氏症基因
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Application of a C. elegans Dopamine Neuron Degeneration Assay for the Validation of Potential Parkinson’s Disease Genes
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一个线虫多巴胺神经元退化含量的应用验证潜在的帕金森氏症基因
DOI:
10.3791/835-v
•
08:42 min
•
July 18, 2008
•
Laura A. Berkowitz
,
Shusei Hamamichi
,
Adam L. Knight
,
Adam J. Harrington
,
Guy A. Caldwell
,
Kim A. Caldwell
1
Department of Biological Sciences
,
University of Alabama
Chapters
00:26
Introduction
01:44
Performing Genetic Crosses for Dopamine Neurodegeneration Analysis
03:51
Performing Dopaminergic Neuron Analysis
07:49
Conclusion
Summary
Automatic Translation
English (Original)
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Automatic Translation
该视频演示如何使用线虫作为帕金森病模型的多巴胺能神经元的神经退行性疾病,以评估。此外,遗传屏幕是用来识别,要么提高变性或神经因素。
Tags
C. Elegans
Dopamine Neuron Degeneration Assay
Parkinson’s Disease Genes
Diagnosis
Treatment
Susceptibility Factors
Candidate Genes
Polymorphisms
Proteins
Animal Model System
Caenorhabditis Elegans
Dopamine Neurons
Alpha-synuclein
Neurodegeneration
GFP
DA Transporter Promoter (Pdat-1)
TorsinA
RNAi
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