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Measuring Spinal Presynaptic Inhibition in Mice By Dorsal Root Potential Recording In Vivo
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Chapters
- 00:00Title/Introduction
- 02:23Preparations for Experiment
- 03:19Animal Preparation for Recording Procedure
- 06:00Separating Dorsal Roots and Electrode Positioning
- 07:35Example Data
- 08:35Conclusion
GABAergic presynaptic inhibition is a powerful inhibitory mechanism in the spinal cord important for motor and sensory signal integration in spinal cord networks. Underlying primary afferent depolarization can be measured by recording of dorsal root potentials (DRP). Here we demonstrate a method of in vivo recording of DRP in mice.
